The researchers involved in the Tianqiao and Chrissy Chen Institute for Neuroscience at Caltech are united in their shared goal of deepening our understanding of the brain—the most powerful biological and chemical computing machine—as well as how it works at the most basic level and how it fails because of disease or through the aging process.
Scientists and engineers bring broad expertise to the exploration of the brain's structure and function, and their work builds on Caltech's long history of basic scientific discovery that has fundamentally transformed the landscape in neuroscience.
Using the collaborative and interdisciplinary spirit of the Tianqiao and Chrissy Chen Institute for Neuroscience as their driving force, Caltech's researchers are working together to probe the circuity and cells, and the molecular, chemical, and electrical pathways that not only orchestrate the transfer of information through the brain, but ultimately influence its inner workings and how it responds when those processes break down. They are investigating the fundamental aspects of perception, of thought, of emotion, and of action, and working to translate what they learn into developing general principles, therapies, and technologies that will improve the human condition. They are looking at brain function at all scales, and studying similar brain processes across species.
At the Chen Institute at Caltech, researchers are not just at the front line of discovery and understanding of the human mind, they are moving that line forward every day, as they work to make the inconceivable possible.
Professor Markus Meister and his laboratory combine augmented reality technology with computer vision algorithms to create goggles that can help blind people navigate unfamiliar spaces. The Meister lab had great success with initial testing and hopes the technology can one day be offered by places like banks, grocery stores, museums, and more.
Credit: Meister lab, Caltech
3D image of cross section of a brain with the mid section lit up.
Credit: Mike Tyszka, Caltech Brain Imaging Center
The Mazmanian laboratory has described how Bacteroides fragilis in the gut produces beneficial molecules that protect mice from inflammatory bowel disease and autism-like symptoms. Bacteroides fragilis (red) and the epithelial surface (blue) of a mouse colon. Note bacteria in the center of the gut lumen and deep within colonic crypts.