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Magdalena Zernicka-Goetz
Magdalena Zernicka-Goetz
Bren Professor of Biology and Biological Engineering
The Zernicka-Goetz lab investigates molecular and cellular mechanisms underlying the specification of cell lineages and patterning. The mouse embryo is their major model system because this allows them to combine cell biological and molecular genetic approaches with live embryo imaging to study development in a system that is close to human development.
Publications
- Hadas, Ron;Rubinstein, Hernan et al. (2024) Temporal BMP4 effects on mouse embryonic and extraembryonic developmentNature
- Zernicka-Goetz, Magdalena;Hyun, Insoo (2024) Embryo models need consistent ethical oversightNature
- Zhu, Meng;Meglicki, Maciej et al. (2024) Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos to promote robust lineage diversificationNature Structural & Molecular Biology
- Junyent, Sergi;Meglicki, Maciej et al. (2024) The first two blastomeres contribute unequally to the human embryoCell
- Sato, Nanami;Rosa, Viviane S. et al. (2024) Basal delamination during mouse gastrulation primes pluripotent cells for differentiationDevelopmental Cell
- Weatherbee, Bailey A. T.;Weberling, Antonia et al. (2024) Distinct pathways drive anterior hypoblast specification in the implanting human embryoNature Cell Biology
- Handford, Charlotte E;Junyent, Sergi et al. (2024) Topical section: embryonic models (2023) for Current Opinion in Genetics & DevelopmentCurrent Opinion in Genetics & Development
- Zernicka-Goetz, Magdalena (2023) The evolution of embryo modelsNature Methods
- Lau, Kasey Y. C.;Amadei, Gianluca et al. (2023) Assembly of complete mouse embryo models from embryonic and induced stem cell types in vitroNature Protocols
- Bao, Min;Cornwall-Scoones, Jake et al. (2023) Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tensionNature Cell Biology