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Angelike Stathopoulos
Angelike Stathopoulos
Professor of Biology, Director, Center for Molecular and Cellular Neuroscience
Stathopoulos studies the cis-regulatory mechanisms that drive differential patterning in embryos and other tissues. Her lab is interested in questions such as how do transcription factors act in combination at cis-regulatory modules to support patterns of expression? Or how do cis-regulatory modules located on non-contiguous stretches of DNA coordinate their temporal action? Also, they are interested in how patterning of distinct cell types in the embryo controls cells' behaviors.
Publications
- Pimmett, Virginia L;McGehee, James et al. (2024) Optogenetic manipulation of nuclear Dorsal reveals temporal requirements and consequences for transcription
- Sun, Jingjing;Durmaz, Ayse Damla et al. (2024) Two sequential gene expression programs bridged by cell division support long-distance collective cell migrationDevelopment
- Sun, Jingjing;Zhang, Chen et al. (2023) Single-cell transcriptomics illuminates regulatory steps driving anterior-posterior patterning of Drosophila embryonic mesodermCell Reports
- Macabenta, Frank;Sun, Hsuan-Te et al. (2022) BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migrationDevelopmental Cell
- Dunipace, Leslie;Newcomb, Susan et al. (2022) Brinker levels regulated by a promoter proximal element support germ cell homeostasisDevelopment
- Ákos, Zsuzsa;Dunipace, Leslie et al. (2021) NaNuTrap: a technique for in vivo cell nucleus labelling using nanobodiesDevelopment
- Stevens, Leslie M.;Kim, Goheun et al. (2021) Light-dependent N-end rule-mediated disruption of protein function in Saccharomyces cerevisiae and Drosophila melanogasterPLOS Genetics
- Irizarry, Jihyun;McGehee, James et al. (2021) High levels of Dorsal transcription factor downregulate, not promote, snail expression by regulating enhancer action
- Irizarry, Jihyun;Stathopoulos, Angelike (2021) Dynamic patterning by morphogens illuminated by cis-regulatory studiesDevelopment
- Stepanik, Vincent;Sun, Jingjing et al. (2020) FGF Pyramus Has a Transmembrane Domain and Cell-Autonomous Function in PolarityCurrent Biology